Jan 282019
 

Toxicology and Drugs is a essential part of MRCP exam carrying 16 marks in the exam. Most student usual attain low marks in this section. Toxicology and Drugs is the study of  the nature, effects, and detection of poisons. Medicos Library has provided high standard Toxicology and Drugs on examination revision materials for medical exams.

Clinical pharmacology, therapeutics and clinical toxicology

  • Pharmacology
    - Mechanisms by which drugs produce their pharmacological effects
    - Basic principles of agonism and antagonism
    - Clinical implication of drugs that act at different receptor sites
    - Links between the pharmacological effects of drugs at the molecular level, the cellular level, and the tissue / organ level, and how these are affected by disease processes and other drugs
    - Principles by which both therapeutic and adverse effects occur
  • Clinical pharmacokinetics
    - Processes of drug absorption and distribution
    - Bio-transformation and excretion
    - Concepts of drug half-life and clearance
    - First order and zero order kinetics
  • Monitoring drug therapy
    - Direct measurement of therapeutic response
    - Measurement of plasma drug concentrations
    - Scientific basis for the measurement of drug concentration and its link to the principles of pharmacokinetics
  • Adverse drug reactions
    - Epidemiology of adverse drug reactions: recognition and avoidance
    - Important adverse effects of commonly used drugs
    - Importance of adverse drug reaction reporting schemes
  • Drug interactions
    - Adverse drug interactions and mechanisms by which interaction may occur
    - Common drug interactions and their clinical consequences
  • Pharmacogenetics
    - Principles of pharmacogenetics and its importance in determining variations in response to drugs in man, both in term of efficacy and toxicity
    - Clinical consequences of the common pharmacogenetic variations relevant to clinical practice
  • Therapeutics for specific patient groups
    - Principles of therapeutics as they apply in the following circumstances:
    The elderly
     Pregnancy and breast feeding
    — Patients with renal disease
     Patients with hepatic disease
    —– Effects of these altered physiology on the pharmacokinetics and pharmacodynamics of drugs
    —–
     Principle underlying drug choice, in pregnancy and breast feeding
    —–
     Teratogenic effects of drugs that may be used in pregnancy – Drugs that may produce toxicity in the case of renal and hepatic disease
  • Clinical toxicology
    - Principle of management of patients poisoned by drugs or other toxic substances
    - Assessment, recognition of common symptom patterns
    - Principles of removal of toxic substances
    - Antidotes where these approaches may be appropriate
  • Criteria for selecting drugs in a therapeutic class
    - Criteria used to select a drug from among drugs in a popular therapeutic class including:
    Differences in pharmacokinetics and pharmacodynamics
     The approved indications of the drug 
     Possible adverse effects or drug inteactions 
     Cost effectiveness 
    —–
     Nomenclature
    —– Used to describing studies that may be used to underpin drug selection
  • Drug formulations and routes of administration
    - Various formulations of medicines available
    - Routes by which medicines may be administered
    - Advantages and disadvantages of various routes and preparation
    - Most appropriate formulation selection and drug administration in common clinical scenarios

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 282019
 

Rheumatology is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Rheumatology is the study of rheumatism, arthritis, and other disorders of the joints, muscles, and ligaments. Medicos Library has provided high standard Rheumatology on examination revision materials for medical exams.

  • Basic principles of the common musculoskeletal conditions
  • Clinical science
    - Basic physiology, biochemistry, anatomy and pathology relating to musculoskeletal diseases
    - Pathology of the common rheumatic conditions
  • Clinical conditions
    - Relative prevalence and major associations of the common rheumatological conditions
    - Symptoms and signs of the rheumatic diseases
    - Arthritis associated with other medical conditions
  • Investigations
    - Investigations relevant to the diagnosis and assessment of rheumatic diseases including
    - Acute phase proteins
    - Immunological tests relating to the connective tissue diseases
    - Contemporary imaging techniques
  • Management
    - Management of acute rheumatological emergencies including Septic arthritis, Osteomyelitis, temporal arteritis and acute spinal cord compression
    - Management of rheumatic diseases

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 282019
 

Respiratory is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Respiratory is the study of that deals with the causes, diagnosis, prevention and treatment of diseases affecting the lungs. Medicos Library has provided high standard Respiratory on examination revision materials for medical exams.

  • Anatomy and physiology
    - Clinical relevant anatomy of the upper and lower respiratory tract and thorax including radiological anatomy
    - Principles of respiratory physiology including: How respiration is controlled 
    Principles of gas exchange and oxygen transport
     Ventilation-perfusion relationships
     Lung volumes and transfer factor
    Respiratory aspects of sleep and exercise physiology
    - Physical, humoral and cellular aspects of respiratory defence mechanisms
    - Physiology of the proteinase inhibitors and pulmonary surfactant
  • Pathophysiology and pathology
    - Effects of disease on pulmonary physiology and anatomy including:
    The pulmonary and bronchial circulations as gas exchange
     Adaptations to chronic hypoxaemia
     Pleural fluid production and reabsorption
    - Application of the basic immunological processes to pulmonary pathology including:
     Asthma
    Alveolitis
     Tuberculosis
    - Humoral and cellular immunodeficiency states and sequelae
    - Microbiology of acute and chronic respiratory infections
  • Cell biology and genetics
    - Lung inflammation and repair
    - Vasculitis
    - Cystic fibrosis
    - Anti-protease deficiency
  • Clinical pharmacology
    - Indications for, and mechanisms of action of, drugs used in respiratory disease together with their interactions and side effects.
    - Important respiratory complications of other drugs (NSAIDs and beta blockers)

Clinical conditions
- Clinical features, investigation and management of respiratory disease likely to be encountered by a general physician
Ex:
 Pleural effusion
 Chest pain
Haemoptysis
 Breathlessness
- Impact of systemic disease on the respiratory system
Ex:
 Vasculitis
 Neuromuscular disease
HIV infection
- Occupational lung disease, particularly asthma, pneumoconiosis and asbestos related disease
- Assessment of respiratory malignant condition
- General principles of oncological management including indication of surgery Indications for specialised investigations including bronchoscopy, CT scanning, lung biopsy, lung volumes and exercise testing
- Investigation of sleep related disorders and of the radiological aspects of respiratory diseases
- Indications for, and problems of, lung transplantation
- Control of Mycobacterium tuberculosis infection·
Exclusion
- Knowledge of detailed pulmonary mechanics, oncology drug regimens, drug therapy of environmental mycobacterial infection, inhalation drug kinetics, and detailed histological descriptions is not required.

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 282019
 

Renal/Nephrology is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Renal/Nephrology is the study of normal kidney function and kidney disease, the preservation of kidney health, and the treatment of kidney disease. Medicos Library has provided high standard Renal/Nephrology on examination revision materials for medical exams.

  • Physiology
    - Discrete functions of Glomerular ultrafiltration and tubular function
    - Proximal and distal parts of the nephron, with particular reference to control of water and electrolyte balance
    - Renal tubular acidosis
    - Cystinuria
    - Fluid, electrolyte, and acid-balance disturbances
  • Molecular biology and genetics
    - Genetic defects of common disorders including:
    Polycystic kidney 
    Alport’s syndrome
    Hypophosphataemic rickets
    - Inflammatory injury of the kidney mediated by various cytokines factors
  • Glomerular and tubular disorders
    - Glomerular ultra structure based upon techniques of light microscopy, electron microscopy and immunofluorescence as applied to renal biopsy
    - Primary Glomerular disorders as in idiopathic glomerulonephritis, and nephropathies of systemic diseases
    Ex:
    Diabetes mellitus
    SLE
    Hypertensive nephrosclerosis
    Vasculitis
    Amyloidosis
    - Interstitial nephritis, in particular vase s with reversible aetiology such as drug, heavy metals and analgesics
    - Metabolic sequelae of acute nephrotic and nephritic syndromes
    - Investigation and assessment of Glomerular and tubular disorders, including ultrasonic studies and nuclear medicine
    - Disturbed renal and metabolic functions in nephritic syndrome from a variety of causes
  • Infections of the kidney
    - Management of urinary tract infections including their detention, predisposing factors, prevention, and treatment
    - Anatomical abnormalities leading to repeated urinary tract infection 
    Ex:
    Reflux nephropathy 
    Prostatic hypertrophy
    - Other infections that might affect the kidney by direct invasion or by immune-complex deposition
  • Calculus formation within the urinary tract
    - Metabolic disorders predisposing to stone formation, their investigation, prevention and treatment
    Ex:
    Idiopathic hypercalciuria
    Primary Hyperparathyroidism
    Cystinuria 
    Hyperoxaluria · Acute and chronic renal failure
    - Management of acute and chronic renal failure and of disturbed physiology involved
    - Pathophysiological changes and non-dialytic treatment in different stages of progressive renal failure
    - Principle of nutritional requirements and diatery intervention for patients with chronic renal failure
    - Other therapeutic means to slow down the progression of renal failure
  • Hypertension and renal problems in pregnancy
    - Renal adaptation to pregnancy
    - Management and profylaxis of renal disease and hypertension in pregnancy
  • Drug and the kidney
    - Role of the kidney in the normal elimination of drugs 
    - Mechanisms by which drugs cause nephrotoxic damage
    - Principle of dose adjustment according to residual renal function

Renal replacement therapy
- Different dialysis modalities and their complications
- Complications related to immunosuppressive therapy following renal transplantation

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 282019
 

Infectious disease is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Infectious disease is the study of a disease or disease-causing organism liable to be transmitted to people, organisms, etc. through the environment. Medicos Library has provided high standard Infectious disease on examination revision materials for medical exams.

  • Microbiology
    - Taxonomy of bacteria in terms of Gram-straining and aerobic /anaerobic metabolism
    - Virus classification for members of the herpes group
    - Virus replication with reference to the retroviruses
    - Major pathogenic protozoa and helminths
    Ex:
    -Aerobic or anaerobic bacteria
    -Gram-staining characteristics of bacteria
  • Immunology of infectious diseases
    - Immune deficiency states linked with types of opportunistic infections
    - Principle of immunisation and vaccines currently used
    Ex:
    - Opportunistic infections
    - Immunisation policy
  • Pathophysiology
    - Septic shock
    - ARDS
    - Role of cytokines in infection
  • Epidemiology
    -
    Principles relevant to infectious diseases
    Ex:
    - Mechanisms of transmission of pathogens
    - How epidemics happen
    - Knowledge of carrier states, reservoirs, vectors and zoonoses
    - Elementary concepts of the control of communicable diseases (including immunisation, isolation, contact tracing, chemoprophylaxis of close contacts)
    - Geographical variation in diseases including TB, HIV, Hepatitis B, malaria
  • Treatment
    - Broad indications for commonly employed antimicrobial agents
    - Major adverse effects for commonly employed antimicrobial agents
    Ex:
    - B-lactams
    - Tetracyclines
    - Macrolides
    - Aminoglycosides
    - Quinolines
    - Trimethoprim
    - Metronidazole
    - Antituberculous drugs
    - Antimalarial drugs
    - Antiviral agents

Specific infections
- Characteristics, recognition, prevention, eradication, and pathological effects of all commonly encountered bacteria, viruses, rickettsia, fungi, protozoa, parasites and toxins.
- Principle of infection control
- Differential diagnostic and appropriate investigations
- Presumptive therapies indications
Ex:
- Septicaemia
- Meningitis and encephalitis
- Endocarditis
- Pneumonia (community-acquired, hospital-acquired, lung abscess, empyema)
- Tuberculosis
- PUO (appropriate investigations, when empirical therapy might be indicated)
- Soft-tissue infection and Osteomyelitis
- Streptococcal infection, rheumatic fever, nephritis
- Intra-abdominal sepsis
- Food-poisoning
- Tropical Infections (especially malaria, bilharzias, amoebiasis, filariasis, leishmaniasis, hookworm and viral haemorrhagic fevers)
- Viral hepatitis
- HIV/AIDS (course of typical infection, CD4 count and HIV viral load as markers of progression; main opportunistic infections including Pneumocytis pneumonia, CNS toxoplasmosis, cryptococcal meningitis, tuberculosis)
- Glandular fever syndrome and its differentiation from HIV seroconversion illness
- Spirochaetosis – syphilis, leptospirosis, borrelia
- Toxic shock syndrome and staphylococcal infections

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 282019
 

Gastroenterology is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Gastroenterology is the study of the normal function and diseases of the esophagus, stomach, small intestine, colon and rectum, pancreas, gallbladder, bile ducts and liver. Medicos Library has provided high standard Gastroenterology on examination revision materials for medical exams.

  • Clinical science
    - Structure and function of the gastrointestinal and hepatobilary tract
    - Neurohormonal control of gut motility
    - Secretory and absorptive functions of the gastro-intestinal tract and liver
    - Symptoms and signs of gastrointestinal, hepatobiliary and pancreatic diseases
    - Genetics of the more common gastrointestinal and liver disorders
    - Clinical pharmacology of drugs used in gastrointestinal disorders including their actions, interactions and adverse effects
  • Clinical nutrition
    - Nutritional requirements in health
    - Assessment of nutritional status
    - Nutritional deficiency states
    - Primary nutritional disorders
  • Disorders of the mouth, tongue and salivary glands
    - Mouth ulcers, periodontal and salivary disorders
    - Oral manifestations of systemic and dermatological disorders
  • Disorders of the oesophagus and stomach
    - Alchalasia
    - Carcinomas
    - Peptic ulceration
    - Gastritis
    - Gastrointestinal haemorrhage
  • Functional disorders
    - Functional chest pain and functional dyspepsia
    - Irritable bowel syndrome and functional abdominal pain
    - Functional constipation and diarrhoea
  • Disorders of the small intestine
    - Malabsoption syndromes and gluten enteropathy
    - Hormone-secreting tumours of the gut
  • Disorders of the liver, biliary tree and pancreas
    - Bilirubin metabolism and the enterohepatic circulation of bile acids
    - Causes of jaundice and cholestasis
    - Common pancreatic disorders including carcinoma
    - Fulminant liver failure
    - Acute and chronic hepatitis
    - Drugs, toxins, alcohol and the liver
  • The acute abdomen
    - Perforated viscus and peritonitis
    - Intestinal obstruction
    - Ischaemic disease of the small and large bowel
  • Inflammatory bowel diseases
    - Crohn’s disease
    - Ulcerative colitis
    - Infective gastroenteritis
    - Parasitic and protozoal gut infections

Colorectal disorders
- Polyps
- Carcinomas
- Diverticular disease
- Anorectal disorders

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 222019
 

Endocrinology is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Endocrinology is the study of the endocrine system in the human body. This is a system of glands which secrete hormones. Hormones are chemicals which affect the actions of different organ systems in the body. Examples include thyroid hormone, growth hormone, and insulin. Medicos Library has provided high standard Endocrinology on examination revision materials for medical exams.

  • Mechanisms of hormone action and importance of
  • Receptors and substances involved in control of intracellular metabolism
  • Clinically relevant anatomical aspects of the speciality
  • Thyroid
    - Mechanisms of thyroid disease
    - Clinical presentation and treatment
    Ex:
    Thyroid hormone biosynthesis and its control
    Important drugs interfering with thyroid function 
    Indications for use of various types of thyroid function test
    Autoimmunity and the thyroid
    Clinical features of thyrotoxicosis and hypothyroidism
    Goitre and its management
    Thyroid neoplasia
  • Hypothalamus/Pituitary
    - Physiology and testing of the control mechanisms of the endocrine system
    Ex:
    The physiology and Pathophysiology of control of pituitary hormone secretion
    The mechanisms of maintaining plasma osmolality 
    Tests of pituitary diseases such as acromegaly, prolactinoma and Cushing’s syndrome
    Drugs used in the treatment of pituitary disease
    Pituitary replacement therapy
  • Adrenal
    - Clinically relevant mechanisms of steroid biosynthesis
    Ex:
    Build-up of precursor compounds when there is defective cortisol biosynthesis in adrenocortical hyperplasia
    Tests for adrenocortical function
    Endocrine causes of hypertension and their differential diagnosis
    Clinical features and management of adrenal hyper- and hypofunction
    Complications of steroid therapy
  • Ovary
    - Physiology of ovarian functions
    - Conditions presenting to a physician
    Ex:
    Hormonal changes across the menstrual cycle
    Physiological changes in pregnancy
    The differential diagnosis of hirsutism and virilism
    Causes of amenorrhoea and anovulation
    Endocrine causes of infertility
  • Testis
    - Relevant investigations of urological infertility
    - Endocrine aspects of testicular functions
  • Growth
    - Factors controlling growth hormone secretion
    - Normal growth patterns
    - General medical and endocrine causes of short stature
    - Control of excessive growth
    - Growth hormone therapy and its complications
  • Parathyroid/bone
    - Control of bone turnover and disorders which can result of its failure
    Ex:
    Control of calcium metabolism
    Laboratory tests of parathyroid function
    The causes of hypercalcaemia
    Mechanisms of oesteomalacia
    Hyperparathyroidism, both primary and secondary
    The differentiation of primary, secondary and pseudo-hypoparathyroidism
    The differentiation of primary, secondary and pseudo-hypoparathyroidism
    The prophylaxis and treatment of osteoporosis
    Calcitonin and its role in metabolism
  • Diabetes mellitus
    - Detailed knowledge is required.
    Ex:
    Control of carbohydrate metabolism
    Genetics of diabetes
    Aetiology of type I diabetes and type 2 diabetes
    Long-term complications of diabetes
    Management of diabetic emergencies
    Differential diagnosis and treatment of hypoglycaemia

Disorders of lipid metabolism
- Importance of this group disorder
Ex:
Control of cholesterol metabolism
Aetiology of different types of hyperlipidaemia including both cholesterol and triglyceride disorders
Indications for lipid lowering agents and their complications
Types of secondary hyperlipidaemia

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 222019
 

Emergency and Critical care is a essential part of MRCP exam. Every subject has certain conditions which are considered as acute emergency cases. Emergency and Critical care is the study inpatient and outpatient hospital services necessary to prevent the death or serious impairment of the health of the recipient. Medicos Library has provided high standard Emergency and Critical care on examination revision materials for medical exams.

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 222019
 

Dermatology is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Dermatology is the study of the diagnosis, treatment, and prevention of diseases of the skin, hair, nails, oral cavity and genitals. Medicos Library has provided high standard Dermatology on examination revision materials for medical exams.

  • Basic science
    - Structure and function of the epidermis and dermis
  • Clinical dermatology
    - Recognition of cutaneous symptoms and signs of systemic diseases (diseases affecting internal organs and presenting skin signs or symptoms)
    Ex:
    Collagen vascular disease such as SLE, systemic sclerosis
    Metabolic and endocrine disorders 
    Infectious diseases 
    Cancers 
    Leukaemias 
    Respiratory and cardiovascular diseases
    Common inherited diseases such as neurofibromatosis 
    - Main dermatological complications of therapeutic immunosuppression (ex: systemic corticosteroid therapy, cyclosporin…) or of diseases such as HIV which cause immunosuppression
    - Differential diagnosis and plan of investigation of patients whom, present with the following cutaneous signs or symptoms which may indicate internal diseases:
    Itch 
    Hyperpigmentation
    Generalised erythema
    Loss of hair
    Increased hair growth 
    Common patterns of nail dystrophy such as clubbing
    Erythema nodosum 
    Erythema multiform
    Purpura 
    Ulceration
    Vasculitis 
    - Clinical features of the following skin diseases:
    Psoriasis 
    Eczema
    Urticaria 
    Superficial fungal infections (dermatophytosis, pityriasis versicolor)
    Common skin cancers such as melanoma 
    Vitiligo and alopecia areata
    Pemphigus and pemphigold
    Cutaneous herpes virus infections (herpes simplex, varicella zoster) 
    Cutaneous staphylococcal and streptococcal infections
    Leprosy · Investigation
    - Principles of dermatological investigation such as patch testing

Drugs and therapy
- Drugs which cause life-threatening skin conditions such as
Erythroderma
Stevens-Johnson syndrome, 
Angio-oedema
Toxic epidermal necrolysis

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File

Jan 222019
 

Cardiology is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Cardiology is the study of the heart and blood vessel. Its treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Medicos Library has provided high standard cardiology on examination revision materials for medical exams.

  • Anatomy and physiology
    - Basic anatomy and physiology of the heart in health and disease including:
    Clinical relevant normal anatomy of the heart, coronary arteries and great vessels
     Determinants of the heart rate and rhythm 
     Cardiac conduction 
     Cardiac output
    Vascular tone
     Blood pressure
     Coronary blood flow
     Genesis of heart sound
  • Pathophysiology and pathology
    - Mechanism underlying the main pathological processes
    Ex:
    Thrombosis
     Infarction 
     Atherogenesis
     Hypertrophy
    Heart failure
     Cardiomyopathies
     Dysrhythmias
     Hypertension
  • Cell biology
    - Topics of proven clinical relevance such as:
    Excitation-contraction process
     Molecular and cellular aspects of hypertrophy of the myocardium of vascular smooth muscle
  • Clinical pharmacology
    - Indications of drug therapy in cardiac disease
    - Actions, interactions, and side effects of the drugs used, with emphasis on new drugs and newly observed side effects.
  • Clinical cardiology
    - Clinical features and management of the cardiac disorders encountered in hospital practice by the general physician
    - Risk factors
    Ex:
    Clinical features of constrictive pericarditis, cardiac tamponade, endocarditis, valvular disease 
     Management of acute coronary syndromes
     Management of cardiac failure
    Management issues in atrial fibrillation
     Indications for, and types of, permanent pacemaker
    - Important changes in clinical practice, following the publication of major clinical trials
    Ex:
     Use of ACE inhibitors after myocardial infarction 
     Use of HMG CoA reductase inhibitors in primary and secondary prevention of coronary morbidity and mortality
     Use of beta-adrenoceptor blocking drugs in left ventricular dysfunction
    - Indications for invasive and non-invasive cardiac investigation
    - Principle of these investigative methods, their limitations and the clinical relevance
    Ex:
     Common ECG abnormalities
    Basic echocardiographic abnormalities such as hypertrophic obstructive cardiomyopathy or pericardial effusion
     Indication for coronary angiography

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15
200

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

Click Here to Direct Download   or   Click Here To See The File