Jan 282019

Infectious disease is a essential part of MRCP exam carrying 15 marks in the exam. Most student usual attain low marks in this section. Infectious disease is the study of a disease or disease-causing organism liable to be transmitted to people, organisms, etc. through the environment. Medicos Library has provided high standard Infectious disease on examination revision materials for medical exams.

  • Microbiology
    - Taxonomy of bacteria in terms of Gram-straining and aerobic /anaerobic metabolism
    - Virus classification for members of the herpes group
    - Virus replication with reference to the retroviruses
    - Major pathogenic protozoa and helminths
    -Aerobic or anaerobic bacteria
    -Gram-staining characteristics of bacteria
  • Immunology of infectious diseases
    - Immune deficiency states linked with types of opportunistic infections
    - Principle of immunisation and vaccines currently used
    - Opportunistic infections
    - Immunisation policy
  • Pathophysiology
    - Septic shock
    - ARDS
    - Role of cytokines in infection
  • Epidemiology
    Principles relevant to infectious diseases
    - Mechanisms of transmission of pathogens
    - How epidemics happen
    - Knowledge of carrier states, reservoirs, vectors and zoonoses
    - Elementary concepts of the control of communicable diseases (including immunisation, isolation, contact tracing, chemoprophylaxis of close contacts)
    - Geographical variation in diseases including TB, HIV, Hepatitis B, malaria
  • Treatment
    - Broad indications for commonly employed antimicrobial agents
    - Major adverse effects for commonly employed antimicrobial agents
    - B-lactams
    - Tetracyclines
    - Macrolides
    - Aminoglycosides
    - Quinolines
    - Trimethoprim
    - Metronidazole
    - Antituberculous drugs
    - Antimalarial drugs
    - Antiviral agents

Specific infections
- Characteristics, recognition, prevention, eradication, and pathological effects of all commonly encountered bacteria, viruses, rickettsia, fungi, protozoa, parasites and toxins.
- Principle of infection control
- Differential diagnostic and appropriate investigations
- Presumptive therapies indications
- Septicaemia
- Meningitis and encephalitis
- Endocarditis
- Pneumonia (community-acquired, hospital-acquired, lung abscess, empyema)
- Tuberculosis
- PUO (appropriate investigations, when empirical therapy might be indicated)
- Soft-tissue infection and Osteomyelitis
- Streptococcal infection, rheumatic fever, nephritis
- Intra-abdominal sepsis
- Food-poisoning
- Tropical Infections (especially malaria, bilharzias, amoebiasis, filariasis, leishmaniasis, hookworm and viral haemorrhagic fevers)
- Viral hepatitis
- HIV/AIDS (course of typical infection, CD4 count and HIV viral load as markers of progression; main opportunistic infections including Pneumocytis pneumonia, CNS toxoplasmosis, cryptococcal meningitis, tuberculosis)
- Glandular fever syndrome and its differentiation from HIV seroconversion illness
- Spirochaetosis – syphilis, leptospirosis, borrelia
- Toxic shock syndrome and staphylococcal infections

MRCP(UK) develops and delivers postgraduate medical examinations around the world on behalf of the three Royal Colleges of Physicians of the UK.

Part 1 at a glance

  • one-day examination
  • two three-hour papers
  • 200 mutiple-choice (best of five) questions
  • no images
  • sat in an examination hall.

Exam pass marks

MRCP(UK) examinations

Examination Pass mark
Part 1 540
Part 2 Written 454
PACES 130 (see individual skills breakdown below)

The composition of the papers is as follows:

Specialty Number of questions*
Cardiology 15
Clinical haematology and oncology 15
Clinical Pharmacology, Therapeutics and Toxicology 16
Emergency and Critical care
Clinical sciences** 25
Dermatology 8
Endocrinology 15
Geriatric medicine 4
Gastroenterology 15
Infectious diseases and GUM 15
Neurology 15
Nephrology 15
Ophthalmology 4
Psychiatry 8
Respiratory medicine 15
Rheumatology 15

* This should be taken as an indication of the likely number of questions – the actual number may vary slightly.

** Clinical sciences comprise:

Cell, molecular and membrane biology 2
Clinical anatomy 3
Clinical biochemistry and metabolism 4
Clinical physiology 4
Genetics 3
Immunology 4
Statistics, epidemiology and evidence-based medicine 5

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